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What Is IGF-1 LR3?
IGF-1 LR3 (Long R3 Insulin-like Growth Factor-1) is a modified recombinant peptide that represents an enhanced version of human insulin-like growth factor 1 (IGF-1). This research peptide consists of 83 amino acids, including a 13-amino acid extension at the N-terminus and an arginine substitution at position 3, giving it the “Long R3” designation.
When researchers buy IGF-1 LR3 online for their studies, they’re acquiring a compound specifically engineered to have reduced binding to IGF binding proteins, resulting in significantly extended half-life and enhanced potency compared to native IGF-1 in laboratory settings.
As a synthetic analog of IGF-1, Long R3 IGF-1 has gained significant attention in scientific communities for its potential applications in various research models. When you buy IGF-1 LR3 online, you’re obtaining a peptide that has been studied for its ability to promote cellular growth and metabolism with greater efficiency than standard IGF-1. While native IGF-1 typically has a half-life of just 12-15 minutes in research models, IGF-1 LR3 demonstrates activity for 20-30 hours, making it particularly valuable for extended laboratory investigations.
Recombinant IGF-1 LR3 is available as a lyophilized powder that requires reconstitution before use in laboratory research. Scientists who buy IGF-1 LR3 online typically use it to study growth factor signaling pathways and related cellular mechanisms in controlled laboratory environments.
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When scientists buy IGF-1 LR3 online, they typically focus on several key research areas. This peptide has been extensively studied in laboratory settings for its potential applications in various experimental models:
Cellular Growth Pathway Research
IGF-1 LR3 has been investigated for its effects on cellular growth and proliferation mechanisms in laboratory settings. Research suggests that when IGF-1 LR3 binds to IGF-1 receptors on cell surfaces, it may initiate a cascade of intracellular signaling events, primarily through the PI3K/Akt and MAPK pathways. These events have been studied for their role in stimulating protein synthesis and cell division. Scientists who buy IGF-1 LR3 online often examine these pathways using various in vitro and in vivo experimental models.
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Another area where researchers buy IGF-1 LR3 online is for muscle tissue studies. Laboratory investigations have explored how IGF-1 LR3 interacts with skeletal muscle cells in experimental models. These studies typically examine parameters such as protein synthesis rates, satellite cell activation, and myoblast differentiation under controlled conditions. The peptide’s ability to potentially promote both hyperplasia (increase in cell number) and hypertrophy (increase in cell size) makes it particularly interesting for muscle biology research.
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IGF-1 LR3 has been studied for its interaction with metabolic processes in research settings. Researchers who buy IGF-1 LR3 online may investigate its effects on glucose metabolism, insulin sensitivity, and lipid utilization in laboratory models. These studies contribute to the broader understanding of how growth factors influence metabolic regulation and energy homeostasis.
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The peptide has been examined in various endocrine system research models. Scientists who buy IGF-1 LR3 online often study its interactions with other hormonal systems, including growth hormone and insulin pathways. These investigations help elucidate the complex interplay between different endocrine signals in controlled laboratory settings.
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When researchers buy IGF-1 LR3 online, they frequently use it to study IGF-1 receptor binding characteristics. The peptide has been investigated for its affinity, specificity, and kinetics of interaction with IGF-1 receptors. These studies contribute to the fundamental understanding of structure-activity relationships in growth factor peptides and their receptors.
IGF-1 LR3 Mechanism of Action in Research Settings
Scientists who buy IGF-1 LR3 online are often interested in its mechanism of action, which has been extensively studied in laboratory settings. Research suggests that IGF-1 LR3 primarily works by binding to IGF-1 receptors, which are tyrosine kinase receptors present on the surface of many cell types.
When IGF-1 LR3 binds to IGF-1 receptors in experimental models, it appears to trigger a conformational change in the receptor, leading to autophosphorylation of the receptor’s intracellular domain. This initiates two main signaling cascades: the phosphatidylinositol 3-kinase (PI3K)/Akt pathway and the Ras/mitogen-activated protein kinase (MAPK) pathway.
Research has shown that in laboratory settings, the PI3K/Akt pathway may play a crucial role in protein synthesis, glucose uptake, and cell survival, while the MAPK pathway has been studied for its potential involvement in cell proliferation and differentiation. These dual signaling mechanisms make IGF-1 LR3 a valuable tool for studying complex cellular responses.
Scientists who buy IGF-1 LR3 online for research purposes have also investigated its reduced binding to IGF binding proteins (IGFBPs). Studies suggest that the structural modifications in IGF-1 LR3 significantly decrease its affinity for IGFBPs, potentially allowing more free peptide to interact with receptors and extending its biological activity in experimental models.
Product Specifications: Premium IGF-1 LR3 for Sale
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Available Strengths
- IGF-1 LR3 0.1mg: Our standard research-grade vial containing 0.1mg of lyophilized IGF-1 LR3 peptide
- IGF-1 LR3 1mg: Higher concentration vial containing 1mg of lyophilized IGF-1 LR3 peptide
Product Details
- Purity: >98% (verified by HPLC analysis)
- Form: Lyophilized powder in sealed glass vials
- Sequence: MFPAMPLSSLFVNGPRTLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKSA
- Molecular Formula: C₃₈₁H₆₂₂N₁₁₄O₁₁₅S₆
- Molecular Weight: Approximately 9,111 daltons
- CAS Number: 946870-92-4
- Production Method: Recombinant DNA technology in E. coli
- Batch Testing: Each production batch undergoes comprehensive quality control testing
- Documentation: Certificate of Analysis (COA) available for verification
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Storage & Handling Instructions for IGF-1 LR3
Proper storage and handling are essential when you buy IGF-1 LR3 online for research purposes:
Storage Recommendations
- Lyophilized (Powder) Form:
- Store unopened vials at -20°C (freezer)
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- Keep in original container with lid tightly sealed
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- Reconstituted Solution:
- Store at 2-8°C (refrigerator)
- Use within 14 days for optimal stability
- Avoid repeated freeze-thaw cycles
- Protect from direct light
Handling Precautions
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Reconstitution Guidelines
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- Use bacteriostatic water or sterile acetic acid solution (0.1%)
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- Allow the vial to reach room temperature before reconstitution
- Gently swirl to dissolve; avoid vigorous shaking
- Document reconstitution date and calculated concentration
Frequently Asked Questions About IGF-1 LR3
What is IGF-1 LR3 used for in research?
IGF-1 LR3 is primarily used in laboratory research to study cellular growth and metabolic signaling pathways. Scientists who buy IGF-1 LR3 online typically investigate its interactions with the IGF-1 receptor and subsequent effects on protein synthesis, cell proliferation, and glucose metabolism. It’s also studied in muscle tissue research, metabolic regulation models, and various endocrine system pathways. All research with IGF-1 LR3 should be conducted in appropriate laboratory settings by qualified professionals.
How does IGF-1 LR3 differ from regular IGF-1?
IGF-1 LR3 features significant structural modifications compared to native IGF-1. Researchers who buy IGF-1 LR3 online often note three key differences: 1) It contains a 13-amino acid extension at the N-terminus, 2) It has an arginine substitution at position 3, and 3) These modifications dramatically reduce binding to IGF binding proteins. As a result, IGF-1 LR3 demonstrates a much longer half-life in research settings (20-30 hours versus 12-15 minutes for native IGF-1) and potentially greater potency, making it valuable for extended laboratory studies of IGF-1 signaling pathways.
Is IGF-1 LR3 legal to purchase?
Yes, it is legal to buy IGF-1 LR3 online for research purposes. IGF-1 LR3 peptide for sale is intended exclusively for laboratory research and is not approved for human consumption or veterinary use. Researchers should ensure compliance with local regulations regarding the purchase and use of research peptides. Always review our Terms and Conditions before purchasing.
How should IGF-1 LR3 be stored?
When you buy IGF-1 LR3 online, proper storage is essential for maintaining its stability. Lyophilized (powder) IGF-1 LR3 should be stored in a freezer at -20°C, protected from light and moisture. Once reconstituted, the solution should be kept refrigerated at 2-8°C and used within 14 days for optimal results. Avoid repeated freeze-thaw cycles as they can degrade the peptide’s structure and reduce its effectiveness in research applications.
Is your IGF-1 LR3 lab tested?
Absolutely. All researchers who buy IGF-1 LR3 online from Anabolic Steroid Shop receive products that undergo comprehensive laboratory testing. Each batch is analyzed using High-Performance Liquid Chromatography (HPLC) to verify purity (>98%) and Mass Spectrometry to confirm peptide identity. We provide a Certificate of Analysis (COA) with every purchase, allowing researchers to verify the quality and specifications of their IGF-1 LR3 peptide for sale.
What is the molecular weight of IGF-1 LR3?
IGF-1 LR3 has a molecular weight of approximately 9,111 daltons. This information is important for researchers who buy IGF-1 LR3 online and need to perform precise calculations for their experimental protocols. The peptide consists of 83 amino acids, including the 13-amino acid extension at the N-terminus and the arginine substitution at position 3, contributing to its molecular structure and weight.
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In laboratory settings, IGF-1 LR3 is typically reconstituted with bacteriostatic water or a sterile 0.1% acetic acid solution. Researchers who buy IGF-1 LR3 online should calculate the desired concentration based on their specific experimental protocols. The reconstitution process should be performed using aseptic technique, allowing the vial to reach room temperature before adding the diluent, and gently swirling to ensure complete dissolution without damaging the peptide structure.
What is the difference between IGF-1 LR3 0.1mg and IGF-1 LR3 1mg vials?
The difference is simply the amount of IGF-1 LR3 peptide contained in each vial. When you buy IGF-1 LR3 online, you can choose between 0.1mg or 1mg vials based on your research needs. The 0.1mg vial is suitable for smaller-scale experiments or when testing new protocols, while the 1mg vial offers better value for established research programs with higher volume requirements. Both contain the same high-purity IGF-1 LR3 peptide, just in different quantities.
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Additional Research Information on IGF-1 LR3
IGF-1 LR3 in Scientific Literature
The scientific community continues to explore the properties and potential applications of IGF-1 LR3 in various research models. When you buy IGF-1 LR3 online for laboratory investigations, you’re working with a peptide that has been the subject of numerous scientific publications.
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Scientists who buy IGF-1 LR3 online often cite its well-characterized receptor binding profile and consistent effects in laboratory models as advantages for research applications. The peptide’s enhanced stability and reduced binding to IGF binding proteins also make it suitable for various experimental protocols requiring extended exposure times.
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IGF-1 LR3 is an 83-amino acid polypeptide with a molecular weight of approximately 9,111 daltons. Researchers who buy IGF-1 LR3 online may be interested in its structural features that contribute to its enhanced properties:
- The 13-amino acid N-terminal extension (MFPAMPLSSLFVN) increases stability and reduces binding to IGF binding proteins
- The arginine substitution at position 3 (hence the “R3” designation) further modifies binding characteristics
- The core IGF-1 sequence maintains the essential receptor binding domains
- The tertiary structure includes three disulfide bridges that stabilize the three-dimensional conformation
These structural characteristics make IGF-1 LR3 a valuable tool for researchers studying growth factor signaling pathways and cellular responses to IGF-1 receptor activation.
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Scientists who buy IGF-1 LR3 online often use it alongside native IGF-1 to conduct comparative studies. Such investigations may examine differences in receptor binding, signaling pathway activation, or cellular responses in laboratory models.
Comparative studies between IGF-1 LR3 and native IGF-1 help researchers understand the impact of binding protein interactions on growth factor activity. These investigations contribute to the broader understanding of IGF-1 regulation and related physiological processes.
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